Textbooks

Optical Coherence Tomography in Dentistry Scientific Developments to Clinical Applications (Textbook)

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Optical Coherence Tomography (OCT), a method to "see inside of things" without destroying them, has been applied to subjects ranging from materials science to medicine. This book focuses on the biomedical application of OCT in dentistry, covering topics from dental materials to clinical practice.   Since the introduction of the OCT method in ophthalmology and then dentistry in 1991, developments in OCT methods, particularly in biomedical areas, have led to its dissemination worldwide. The chapters of this book cover the basics and recent global advances of OCT in dentistry, including an overview of the method and its use in cariology, restorative dentistry, dental materials, endodontics, pediatric dentistry, orthodontics, prosthodontics, soft oral tissues, and nanodentistry.   This book will be of interest to both newcomers in the field as well as those already working in OTC, either in research and/or the clinic. It will be of great use in courses on optical imaging...

Advances in Biomedical Photonics (Textbook)

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In Biomedical Photonic Technologies, a team of distinguished researchers delivers a methodical inquiry and evaluation of the latest developments in the field of biomedical photonics, with a focus on novel technologies, including optical microscopy, optical coherence tomography, fluorescence imaging-guided surgery, photodynamic therapy dosimetry, and optical theranostic technologies. Each discussion of individual technologies includes examples of their contemporary application in areas like cancer therapy and drug delivery. Readers will discover the major research advancements in biomedical photonics from the last 20 years, ascertaining the basic principles of formation, development, and derivation of biomedical photonics phenomena at a variety of scales. Readers will also find:

Optical coherence microscopy with a split-spectrum image reconstruction method for temporal-dynamics contrast-based imaging of intracellular motility

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Optical coherence microscopy with a split-spectrum image reconstruction method for temporal-dynamics contrast-based imaging of intracellular motility Biomedical researchers use optical coherence microscopy (OCM) for its high resolution in real-time label-free tomographic imaging. However, OCM lacks bioactivity-related functional contrast. We developed an OCM system that can measure changes in intracellular motility (indicating cellular process states) via pixel-wise calculations of intensity fluctuations from metabolic activity of intracellular components. To reduce image noise, the source spectrum is split into five using Gaussian windows with 50% of the full bandwidth. The technique verified that F-actin fiber inhibition by Y-27632 reduces intracellular motility. This finding could be used to search for other intracellular-motility-associated therapeutic strategies for cardiovascular diseases.

Photo Acoustic and Optical Coherence Tomography Imaging, Volume 2 (Textbook)

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This book covers the state-of-the-art techniques of fundus imaging for the diagnosis of retinal diseases. It is part of a three-volume work that describes the latest imaging techniques in which to bring optical coherence tomography (OCT), fundus Imaging and optical coherence tomography angiography (OCTA) to accurately facilitate the diagnosis of retinal diseases. Clinical disorders of the retina have been attracting the attention of researchers, aiming at reducing the blindness rate. This includes uveitis, diabetic retinopathy, macular edema, endophthalmitis, proliferative retinopathy, age-related macular degeneration and glaucoma. Treatment is significantly dependent on having early and accurate diagnosis, which can be significantly improved by employing the techniques described in the book.

Optical coherence tomography (Book Chapter)

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Optical coherence tomography (OCT) is a non-invasive optical method that is able to inspect beneath the surface of low-scattering media. OCT retrieves high resolution cross-sectional images employing light, making it possible to observe internal echoes corresponding to an object's structural information. It was first used for optical fiber inspection, but it quickly found use in the medical field, particularly in ophthalmology. It is now applied in a broad spectrum of engineering and medical fields.

Optical Coherence Tomography of the Anterior Segment (Textbook)

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This book is a highly illustrated, practical guide to anterior segment optical coherence tomography (OCT) with numerous photographs and didactic information throughout. Clear and concise chapters outline the diagnostics of the anterior segment of the eye with clinical advice given to support ophthalmic surgeons with pre and intraoperative surgery planning as well as postoperative follow-up care. Optical Coherence Tomography of the Anterior Segment will be a useful resource for everyday practice to allow clinicians to grow their expertise in this patient-friendly and common diagnostic procedure. As the procedure continues to gain popularity, this book will be an indispensable resource for all levels of ophthalmologist who wish to improve their knowledge and techniques of anterior segment OCT.

Atlas of Ocular Optical Coherence Tomography, 2nd Edition (Textbook)

(1) Basics and principles of optical coherence tomography (OCT), which briefly discuss the mechanisms and operation of OCT systems and a comparison of old and new systems (time domain vs. spectral domain) and their reproducibility. It concisely explains the swept-source OCT mechanism and OCT angiography as well. (2) Normal OCT, which describes normal findings and variations that are expected on normal OCT images, and the layers of the normal retina and in different parts of the posterior segment. (3) Enhanced-depth imaging (EDI)-OCT and its applications and indications in various diseases such as choroidal tumors, age-related macular degeneration, diabetic retinopathy, central serous chorioretinopathy, glaucoma, intraocular inflammation, and myopia. Moreover, choroidal measurement and its variations under different conditions are discussed. (4) Limitations and indications of OCT, which evaluate and explain the drawbacks and advantages of this diagnostic method for the exploration of...

Diabetic Macular Edema (Textbook)

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The book focuses on diabetic macular edema and provides comprehensive practical knowledge on the subject. This timely book summarizes all the aspects of diabetic macular edema. The book is edited by leading authorities of vitreoretinal diseases having expertise in diabetic macular edema. It comprises over dozen chapters, authored by a subject authority in the world. Chapters provide diagnostic, medical and surgical approach. The book is clinically relevant, covers application of the latest clinical trials as well as application of novel imaging technologies. It includes uniquely structured chapters for easy learning. The book is beneficial to ophthalmic resident doctors, retina fellows and practicing retina specialists throughout the world.

The Use of Optical Coherence Tomography in Evaluation of Retinitis Pigmentosa (Book Chapter)

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Optical coherence tomography (OCT) is a noninvasive imaging technology that has gained widespread use in the evaluation of multiple retinal pathologies, including retinitis pigmentosa (RP). OCT allows for visualization of distinct retinal layers and the choroid and facilitates study of morphological features associated with RP. OCT can be used to detect and to track progression of RP, as well as to correlate structural findings with functional manifestations of the disease. This chapter provides a basic overview of OCT technology and details elements of importance in the use of OCT for diagnosis and assessment of progression of RP. ( Read Full Article )

Optical Coherence Tomography in Brain Gliomas Detection and Peritumoral White Matter State Evaluation (Book Chapter)

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Optical coherence tomography (OCT) is a rapidly emerging visualization method providing real-time detailed information about the biological tissues structure without any contrast agents based on the backscattered light detection. In this chapter, we discuss the perspectives of application of OCT in brain glioma surgery. The reader can get acquainted with the problems arising in brain tumor surgery and the possibility of using OCT to solve them. The information about the types of OCT data collected in neurosurgery, approaches for their assessment as well as main features of OCT signal representative for different brain tissue types are presented in the chapter. In addition to the perspectives of using OCT for differentiating tumor and healthy brain tissues, we also demonstrate the possibility of using this technology to evaluate morphological features of white matter in the perifocal area of the tumor and talk about the prospects of using machine learning and artificial intelligence ...

Optical Coherence Tomography Angiography for Biomarker Indices in Diabetes (Book Chapter)

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Optical coherence tomography angiography (OCTA) visualizes the structure and flow of retinal vasculature using motion contrast. Diabetic retinopathy (DR), commonly present in one-third of the patients with diabetes, is a major microvascular complication of diabetes mellitus caused by retinal ischemia and vascular hyperpermeability. Microvasculature changes, such as foveal avascular zone enlargement and decrease in vascular density of the deep capillary plexus, have been identified in diabetic eyes without clinical retinopathy. OCTA of nonproliferative DR shows morphologically well-defined microaneurysms and intraretinal vascular shunts around perfusion dropouts at the deep capillary plexus level. In proliferative DR, OCTA visualizes detailed features and extent of neovascularization in response to anti-vascular endothelial factor and laser treatment. Diabetes-induced microvascular changes can be quantified by OCTA, and significant correlations have been shown with serum biomarkers r...

Optical Coherence Tomography in Glaucoma (Textbook)

Optical coherence tomography (OCT) is a noninvasive diagnostic imaging modality that enables ophthalmologists to visualize different layers of the optic nerve and retinal nerve fiber layer (RNFL) with astounding detail. Today, OCT is an instrumental tool for screening, diagnosing, and tracking the progression of glaucoma in patients. Optical Coherence Tomography in Glaucoma by renowned glaucoma specialist Jullia A. Rosdahl and esteemed contributors is a one-stop, unique resource that summarizes the clinical utility of this imaging technology, from basics to advanced analyses. The book features 14 chapters, starting with introductory chapters that discuss development of OCT and its applications for visualizing the optic nerve and macula. In chapter 5, case studies illustrate OCT imaging of the optic nerve, RNFL, and macula in all stages of glaucoma, from patients at risk to those with mild, moderate, and severe diseases. The next chapters cover the intrinsic relationship between opti...

Optical Coherence Elastography (Textbook)

Optical Coherence Elastography: Imaging Tissue Mechanics on the Micro-Scale provides a unique and practical overview of this important new fi eld, which has seen tremendous growth in the last decade. Using optical coherence tomography (OCT) to measure sample deformation, optical coherence elastography (OCE) provides visualization of the three-dimensional, micro-scale mechanical properties of tissues and biomaterials and has shown distinct promise for application across clinical medicine, biology, and tissue engineering. This timely book provides: • Detailed coverage of the key elements required for the successful implementation of OCE techniques, particularly OCT imaging, mechanical deformation, and image processing • Synthesis of theory, methodology, and applications in one resource • Detailed discussion of the historical context within which OCE has evolved, particularly regarding ultrasound elastography and magnetic resonance elastography • Perspectives on lik...

Photo Acoustic and Optical Coherence Tomography Imaging, Volume 3

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This book covers the state-of-the-art techniques of optical coherence tomography angiography (OCTA) imaging for the diagnosis of retinal diseases. It is part of a three-volume work that describes the latest imaging techniques in which to bring optical coherence tomography (OCT), Fundus Imaging and optical coherence tomography angiography (OCTA) to accurately facilitate the diagnosis of retinal diseases. Clinical disorders of the retina have been attracting the attention of researchers, aiming at reducing the blindness rate. This includes uveitis, diabetic retinopathy, macular edema, endophthalmitis, proliferative retinopathy, age-related macular degeneration and glaucoma. Treatment is significantly dependent on having early and accurate diagnosis, which can be significantly improved by employing the techniques described in the book. ( Read Full Article )

Optical Coherence Tomography in Biomedicine (Book Chapter)

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In this chapter, we first introduce the basic working principles of optical coherence tomography (OCT). Three types of OCT, including time-domain, spectral-domain, and swept-source OCT are discussed. Functional OCT methods, including polarization sensitive OCT (PS-OCT), spectroscopic OCT (S-OCT), optical coherence elastography (OCE), and OCT angiography (OCTA) are also described. Furthermore, recent advances in high-speed and high-resolution OCT technologies are reviewed. We also highlight several OCT applications in biomedicine, including ophthalmology, cardiovascular imaging, and oncology. Continuous innovations and further developments in the OCT field will generate long-lasting research and clinical impact in biology and medicine ( Read Full Article )

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