En Face Optical Coherence Tomography in Diagnosis of Persistent Subretinal Fluid & Outer Retinal Folds after Rhegmatogenous Retinal Detachment Repair

January 24, 2023 | Ophthalmology | Sunnybrook Health Sciences Centre, UCLA, University of Toronto

Aditya Bansal, Alan R. Berger, DAVID SARRAF, David T. Wong, Hesham Hamli, Peter J. Kertes, Radha P. Kohly, Rajeev H. Muni, Roxane J. Hillier, SRINIVAS SADDA, Wei We iLee

Purpose To evaluate the role of en face optical coherence tomography (OCT) as a diagnostic tool for the detection of persistent subretinal fluid (PSRF) and outer retinal folds (ORF) following successful rhegmatogenous retinal detachment (RRD) repair. Design Observational post hoc analysis of two prospective surgical trials. Participants All patients with gradable (signal strength ≥ 5 and no segmentation error) 6x6 mm macular cube scans using spectral-domain OCT (SD-OCT) (Carl Zeiss Meditec, Jena, Germany) obtained between 1 and 2 months postoperatively were included in this study. Methods Scans were assessed for the presence or absence of PSRF or ORFs using en face OCT and cross-sectional B scans by two masked graders with any disagreements adjudicated by the third senior masked grader. Main Outcome Measure Sensitivity, specificity and predictive accuracy {using area under curve (AUC)} of en face OCT in comparison to cross-sectional OCT as the gold standard Results Two hu...