Foveal avascular zone in normal human eyes by optical coherence tomography angiography

January 24, 2023 | Ophthalmology

Guisen Zhang, Guoqiang Zhang, Han Zhang, Huixia Li, Jie She, Xiaoguang Zhang, Yunlei Pan

Objective To analyze the influence factors of the area of superficial plexus foveal avascular zone (FAZ) and related indexes of fovea measured with optical coherence tomography angiography (OCT-A) in normal subjects. Methods This was a cross-sectional study from November 2020 to May 2021 in the Inner Mongolia Autonomous Region, China. Each subject received related eye examination. The correlation between all the factors and superficial plexus FAZ were analyzed under univariable and multivariable linear regression analysis. Results Finally, 239 subjects with sufficient data were recruited in the study, including 108 males and 131 females, aged 27.41±4.63 years. The area of superficial plexus FAZ was 0.33±0.16 mm2. In the univariate regression, gender (β = 41.702, 95%CI: 9.152 to 74.253, P = 0.012), drinking (β = -66.074, 95%CI: -99.197 to -32.951, P = 0.001) and axial length (β = -15.874, 95%CI: -29.562 to -2.185, P = 0.023) were associated with superficial plexus FAZ area. In m...